Genome Organization & Function in the Cell Nucleus
January 2012 - It seemed to take forever but finally the book edited by Karsten has been published. It provides an integrated description of central genome associated processes in the nucleus that combines genomics, chromatin structure, epigenetics and nuclear architecture. more...
Telomeres, RNA & nucleosomes
November 2011 - This fall we successfully finished studies on three important topics of our lab: The alternative telomere lengthening pathway, nuclear architecture by RNA and the regulation of DNA access for transcription factors by nucleosomes. more...
The Genome Organization & Function group at the BioQuant is an interdisciplinary research team from the German Cancer Research Center (DKFZ). We combine molecular/cell biology and physics to develop quantitative descriptions that relate the dynamic organization of the (epi)genome with gene expression programs and functional cell states.
