Selected publications

Selected research articles 1992-2023

Piroeva KV, McDonald C, Xanthopoulos C, Fox C, Clarkson CT, Mallm J-P, Vainshtein Y, Ruje L, Klett LC, Stilgenbauer S, Mertens D, Kostareli E*, Rippe K*, Teif VB* (2023) Nucleosome repositioning in chronic lymphocytic leukaemia. Genome Res 33, 1649-1661. *corresponding authors. doi: 10.1101/gr.277298.122 | Abstract | Reprint | Article metrics

Poos AM, Prokoph N, Przybilla MJ, Mallm J-P, Steiger S, Seufert I, John L, Tirier SM, Bauer K, Baumann A, Munawar U, Rasche L, Kortuem M, Giesen N, Huhn S, Reichert P, Mueller-Tidow C, Goldschmidt H, Stegle O, Raab MS, Rippe K*, Weinhold N* (2023) Resolving therapy resistance mechanisms in multiple myeloma by multiomics subclone analysis. Blood 142, 1633-1646. *corresponding authors. doi: 10.1182/blood.2023019758 | Abstract | Reprint | Article metrics

Trojanowski J, Frank L, Rademacher A, Mücke N, Grigaitis P, Rippe K (2022) Transcription activation is enhanced by multivalent interactions independent of phase separation. Mol Cell 82, 1878-1893. doi: 10.1016/j.molcel.2022.04.017 | Abstract | Reprint | Article metrics

Frank L, Rademacher A, Mücke N, Tirier SM, Koeleman E, Knotz C, Schumacher S, Stainczyk SA, Westermann F, Fröhling S, Chudasama P, Rippe K (2022) ALT-FISH quantifies alternative lengthening of telomeres activity by imaging of single-stranded repeats. Nucleic Acids Res, gkac113. doi: 10.1093/nar/gkac113 | Abstract | Reprint | Article metrics

Tirier SM, Mallm J-P, Steiger S, Poos AM, Awwad M, Giesen N, Casiraghi N, Susak H, Bauer K, Baumann A, John L, Seckinger A, Hose D, Müller-Tidow C, Goldschmidt H, Stegle O, Hundemer M, Weinhold N, Raab MS, Rippe K (2021) Subclone specific microenvironmental impact and drug response in refractory multiple myeloma revealed by single cell transcriptomics. Nat Commun 12, 6960. doi: 10.1038/s41467-021-26951-z | Abstract | Reprint | Article metrics

Erdel F, Rademacher A, Vlijm R, Tünnermann J, Schweigert E, Frank L, Yserantant K, Hummert J, Bauer C, Schumacher S, Weinmann R, Alwash AA, Normand C, Herten D-P, Engelhardt J, Rippe K (2020) Mouse heterochromatin adopts digital compaction states without showing hallmarks of HP1-driven liquid-liquid phase separation. Mol Cell 78, 236-249.e7. doi: 10.1016/j.molcel.2020.02.005 | Abstract | Reprint (6.2 MB) | Article metrics | Comment

Mallm JP, Windisch P, Biran A, Schumacher S, Glass R, Herold-Mende C, Meshorer E, Barbus M, Rippe K (2020) Glioblastoma initiating cells are sensitive to histone demethylase inhibition due to loss of DNA repair capacity. Intl J Cancer 146, 1281-1292. doi: 10.1002/ijc.32649 | Abstract | Reprint (6.6 MB) | Article metrics

Mallm JP, Iskar M, Ishaque N, Klett LC, Kugler SJ, Muino JM, Teif VB, Poos AM, Großmann S, Erdel F, Tavernari D, Koser SD, Schumacher S, Brors B, König R, Remondini D, Vingron M, Stilgenbauer S, Lichter P, Zapatka M, Mertens D & Rippe K (2019) Linking aberrant chromatin features in chronic lymphocytic leukemia to deregulated transcription factor networks. Mol Syst Biol 15, e8339. doi: 10.15252/msb.20188339 | Abstract | Reprint (7.1 MB) | Appendix (6.8 MB) | Additional data | Article metrics

Rademacher A, Erdel F, Trojanowski J, Schumacher S & Rippe K (2017). Real-time observation of light-controlled transcription in living cells. J Cell Sci 130, 4213-4224. doi: 10.1242/jcs.205534 | Abstract | Reprint (12.9 MB) | JCS First person | Article metrics

Wachsmuth M, Knoch TA & Rippe K (2016). Dynamic properties of independent chromatin domains measured by correlation spectroscopy in living cells. Epigenetics Chromatin 9, 57. doi: 10.1186/s13072-016-0093-1 | Abstract | Reprint (5.1 MB) | Article metrics.

Caudron-Herger M, Pankert T, Seiler J, Nemeth A, Voit R, Grummt I & Rippe K (2015). Alu element-containing RNAs maintain nucleolar structure and function. EMBO J 34, 2758-2771. doi: 10.15252/embj.201591458 | Abstract | Reprint (4.6 MB) | Comment | Cover | Article metrics

Mallm JP & Rippe K (2015). Aurora kinase B regulates telomerase activity via a centromeric RNA in stem cells. Cell Rep 11, 1667-1678. doi: 10.1016/j.celrep.2015.05.015 | Abstract | Reprint (5.9 MB) | Article metrics

Osterwald S, Deeg KI, Chung I, Parisotto D, Wörz S, Rohr K, Erfle H & Rippe K (2015). PML induces compaction, partial TRF2 depletion and DNA damage signaling at telomeres and promotes alternative lengthening of telomeres. J Cell Sci 128, 1887-1900. doi: 10.1242/jcs.148296 | Abstract | Reprint (4.3 MB) | Article metrics

Müller-Ott K, Erdel F, Matveeva A, Hahn M, Mallm, JP, Rademacher A, Marth C, Zhang Q, Kaltofen S, Schotta G, Höfer T & Rippe K (2014). Specificity, propagation and memory of pericentric heterochromatin. Mol Syst Biol 10, 746. doi: 10.15252/msb.20145377 | Abstract | Reprint (7.4 MB) | Article metrics

Baum M, Wachsmuth M, Erdel F & Rippe K (2014). Retrieving the intracellular topology from multi-scale protein mobility mapping in living cells. Nat Commun 5, 4494. doi: 10.1038/ncomms5494 | Abstract | Reprint (6.4 MB) | Article metrics

Teif VB, Beshnova DA, Vainshtein Y, Marth C, Mallm JP, Höfer T & Rippe K (2014). Nucleosome repositioning links DNA (de)methylation and differential CTCF binding during stem cell development. Genome Res 24, 1285-1295. doi: 10.1101/gr.164418.113 | Abstract | Reprint (3.3 MB) | Article metrics

Erdel F & Rippe K (2012). Quantifying transient binding of ISWI chromatin remodelers in living cells by pixel-wise photobleaching profile evolution analysis. Proc Natl Acad Sci USA 109, E3221-E3230. doi: 10.1073/pnas.1209579109 | Abstract | Reprint (3.4 MB) | Article metrics

Teif VB, Vainshtein Y, Caudron-Herger M, Mallm JP, Marth C, Höfer T & Rippe K (2012). Genome-wide nucleosome positioning during embryonic stem cell development. Nat Struct Mol Biol 19, 1185-1191. doi: 10.1038/nsmb.2419 | Abstract | Reprint (7.4 MB) | Article metrics

Chung I, Leonhardt H & Rippe K (2011). De novo assembly of a PML nuclear subcompartment occurs through multiple pathways and induces telomere elongation. J Cell Sci 124, 3603-3618. doi: 10.1242/jcs.084681 | Abstract | Reprint (9.4 MB) | Comment | Article metrics

Ettig R, Kepper N, Stehr R, Wedemann G & Rippe K (2011). Dissecting DNA-histone interactions by molecular dynamics simulations of unwrapping DNA from the nucleosome. Biophys J 101, 1999-2008. doi: 10.1016/j.bpj.2011.07.057 | Abstract | Reprint (5.8 MB) | Article metrics

Erdel F, Schubert T, Marth C, Längst G & Rippe K (2010). Human ISWI chromatin-remodeling complexes sample nucleosomes via transient binding reactions and become immobilized at active sites. Proc Natl Acad Sci USA 107, 19873-19878. doi: 10.1073/pnas.1003438107 | Abstract | Reprint (1.4 MB) | Commtent 1 | Comment 2 | Article metrics

Müller, K. P., Erdel, F., Caudron, M., Marth, C., Fodor, B. D., Richter, M., Scaranaro, M., Beoudoin, J., Wachsmuth, M. & Rippe, K. (2009). A multi-scale analysis of dynamics and interactions of heterochromatin protein 1 in the nucleus by fluorescence fluctuation microscopy. Biophys. J. 97, 2876-2885. Abstract | Reprint (3.3 MB pdf file)

Jegou, T., Chung, I., Heuvelmann, G., Wachsmuth, M., Görisch, S. M., Greulich-Bode, K., Boukamp, P., Lichter, P. & Rippe, K. (2009). Dynamics of telomeres and promyelocytic leukemia nuclear bodies in a telomerase negative human cell line. Mol Biol Cell 20, 2070-2082. Abstract | Reprint (3.3 MB pdf file).

Kepper, N., Foethke, D., Stehr, R., Wedemann, G. & Rippe, K. (2008). Nucleosome geometry and internucleosomal interactions control the chromatin fiber conformation. Biophys. J. 95, 3692–3705. Abstract | Reprint (3.2 MB pdf file)

Rippe, K., Schrader, A., Riede, P., Strohner, R., Lehmann, E. & Längst, G. (2007). DNA sequence- and conformation-directed positioning of nucleosomes by chromatin-remodeling complexes. Proc. Natl. Acad. Sci. USA 104, 15635-15640. Abstract | Reprint (1.4 MB pdf file) | Comment *

Mazurkiewicz, J., Kepert, J. F. & Rippe, K. (2006). On the mechanism of nucleosome assembly by histone chaperone NAP1. J. Biol. Chem. 281, 16462-16472. Abstract | Reprint (2.4 MB pdf file)

Görisch, S. M., Wachsmuth, M., Fejes Tóth, K., Lichter, P. & Rippe, K. (2005). Histone acetylation increases chromatin accessibility. J. Cell Sci. 118, 5825-5834. Abstract | Reprint (0.7 MB pdf file) | Comment *

Fejes Tóth, K., Knoch, T. A., Wachsmuth, M., Stöhr, M., Frank-Stöhr, M., Bacher, C. P., Müller, G. & Rippe, K. (2004). Trichostatin A induced histone acetylation causes decondensation of interphase chromatin. J. Cell Sci. 117, 4277-4287. Abstract | Reprint (0.4 MB pdf file) *

Dekker, J., Rippe, K., Dekker, M. & Kleckner, N. (2002). Capturing chromatin conformation. Science 295, 1306-1311. Abstract | Reprint (0.6 MB pdf file) ***

Rippe, K. (2000). Simultaneous binding of two DNA duplexes to the NtrC-enhancer complex studied by two-color fluorescence cross-correlation spectroscopy. Biochemistry 39, 2131-2139. Abstract | Reprint (0.1 MB pdf file)

Rippe, K., Guthold, M., von Hippel, P. H. & Bustamante, C. (1997). Transcriptional activation via DNA-looping: Visualization of intermediates in the activation pathway of E. coli RNA polymerase-sigma 54 holoenzyme by scanning force microscopy. J. Mol. Biol. 270, 125-138. Abstract | Reprint (4.6 MB pdf file) *

Rippe, K., Fritsch, V., Westhof, E. & Jovin, T. M. (1992). Alternating d(G-A) sequences form a parallel-stranded DNA homoduplex. EMBO J. 11, 3777-3786. Abstract | Reprint (2.2 MB pdf file) *

Selected reviews

Rippe K (2022) Liquid-liquid phase separation in chromatin. Cold Spring Harb Perspect Biol 14, a040683. doi: 10.1101/cshperspect.a040683 | Abstract | Reprint | Article metrics

Erdel F & Rippe K (2018). Formation of chromatin subcompartments by phase separation. Biophys J 114, 2262-2270. doi: 10.1016/j.bpj.2018.03.011 | Abstract | Reprint (0.5 MB) | Article metrics.

Rippe K & Luke B (2015). TERRA and the state of the telomere. Nat Struct Mol Biol 22, 853-858. doi: 10.1038/nsmb.3078 | Abstract | Reprint (1.0 MB) | Article metrics

Cremer T, Cremer M, Hübner B, Strickfaden H, Smeets D, Popken J, Sterr M, Markaki Y, Rippe K & Cremer C (2015). The 4D nucleome: evidence for spatially co-aligned active and inactive nuclear compartments and their functional implications. FEBS Lett 589, 2931-2943. doi: 10.1016/j.febslet.2015.05.037 | Abstract | Reprint (2.2 MB) | Movie S1 | Movie S2 | Movie S3 | Article metrics

Rippe, K., ed. (2012). Genome organization and function in the cell nucleus, 594 pages, Wiley-VCH, Weinheim. ISBN: 3527326987. Abstract | Comment 1 | Comment 2

Chung, I., Osterwald, S., Deeg, K. & Rippe, K. (2012). PML body meets telomere: The beginning of an ALTernate ending. Nucleus 3, 263-275. doi: 10.4161/nucl.20326 | Abstract | Reprint (2.3 MB)

Caudron-Herger, M. & Rippe, K. (2012). Nuclear architecture by RNA. Curr. Opin. Genet. Dev. 22, 187-197. doi: 10.1016/j.gde.2011.12.005 | Abstract | Reprint (1.9 MB)

Rippe, K. (2001). Making contacts on a nucleic acid polymer. Trends Biochem. Sci., 26, 733-740. Abstract | Reprint (0.1 MB pdf file) *

Rippe, K., von Hippel, P. H. & Langowski, J. (1995). Action at a distance: DNA-looping and initiation of transcription. Trends Biochem. Sci. 20, 500-506. Abstract | Reprint (0.8 MB pdf file) **

* These papers have received more than 100 *, 200 ** or 1000 *** citations.


Contact: E-Mail