Publications
Publications
2021
Bulkescher R, Chung I, Eberle JP, Erfle H, Gunkel M, Reymann J, Rippe K, Sauter G, Simon R, Starkuviene V (2021) Multiscale Fluorescent Imaging. In Single-Molecule Science - From Super-Resolution Microscopy to DNA Mapping and Diagnostics, Appasani K, Appasani RK (eds). Cambridge: Cambridge University Press, in press. doi: 10.1017/9781108525909
Frank L, Weinmann R, Erdel F, Trojanowski J, Rippe K (2021) Transcriptional activation of heterochromatin by recruitment of dCas9 activators. In Enhancers and Promoters: Methods and Protocols, Methods in Molecular Biology, Borggrefe T, Daniele Giaimo B (eds), in press.
Hartlieb SA, Sieverling L, Nadler-Holly M, Ziehm M, Toprak UH, Herrmann C, Ishaque N, Okonechnikov K, Gartlgruber M, Park Y-G, Wecht EM, Savelyeva L, Henrich K-O, Rosswog C, Fischer M, Hero B, Jones DTW, Pfaff E, Witt O, Pfister SM, Volckmann R, Koster J, Kiesel K, Rippe K, Taschner-Mandl S, Ambros P, Brors B, Selbach M, Feuerbach L, Westermann F (2021) Alternative lengthening of telomeres in childhood neuroblastoma from genome to proteome. Nat Commun, in press.
2020
Thorn GJ, Clarkson CT, Rademacher A, Mamayusupova H, Schotta G, Rippe K, Teif VB (2020) DNA sequence-dependent formation of heterochromatin nanodomains. bioRxiv 230433. doi: 10.1101/2020.12.20.423673 | Preprint (6 MB) | Article metrics
Bogeska R, Kaschutnig P, Fawaz M, Mikecin AM, Buechler-Schaff M, Paffenholz S, Asada N, Frauhammer F, Buettner F, Ball M, Knoch J, Staeble S, Walter D, Petri A, Correno-Gonzalez M, Wagner V, Brors B, Haas S, Lipka DB, Essers MAG, Holland-Letz T, Mallm JP, Rippe K, Frenette PS, Rieger MA, Milsom MD (2020) Hematopoietic stem cells fail to regenerate following inflammatory challenge. bioRxiv 230433. doi: 10.1101/2020.08.01.230433 | Preprint (7 MB) | Article metrics
Roider T, Seufert J, Uvarovskii A, Frauhammer F, Bordas M, Abedpour N, Stolarczyk M, Mallm, JP, Herbst S, Bruch P, Balke-Want H, Hundemer M, Rippe K, Goeppert B, Seiffert M, Brors B, Mechtersheimer G, Zenz T, Peifer M, Chapuy B, Schlesner M, Müller-Tidow C, Fröhling S, Huber W, Anders S, Dietrich S (2020). Dissecting intratumour heterogeneity of nodal B-cell lymphomas at the transcriptional, genetic and drug-response levels. Nat Cell Biol 22, 896-906. doi: 10.1038/s41556-020-0532-x | Abstract | Reprint (19.9 MB) | Article metrics
Rademacher A, Erdel F, Trojanowski J, Rippe K (2020) Tracing reversible light-induced chromatin binding with near-infrared fluorescent proteins. Meth Mol Biol 2173, 171-188. doi: 10.1007/978-1-0716-0755-8_12 | Abstract | Reprint (0.8 MB) | Article metrics
Solé-Boldo L, Raddatz G, Schütz S, Mallm JP, Rippe K, Lonsdorf AS, Rodríguez-Paredes M, Lyko F (2020). Single-cell transcriptomes of the human skin reveal age-related loss of fibroblast priming. Commun Biol 3, 188. doi: 10.1038/s42003-020-0922-4 | Abstract | Reprint (11.9 MB) | Article metrics
Frank L, Rippe K (2020) Repetitive RNAs as regulators of chromatin-associated subcompartment formation by phase separation. J Mol Biol 432, 4270-4286. doi: 10.1016/j.jmb.2020.04.015 | Abstract | Reprint (1.2 MB) | Article metrics
Wierzbinska JA, Toth R, Ishaque N, Rippe K, Mallm JP, Klett LC, Mertens D, Zenz T, Hielscher T, Seifert M, Küppers R, Assenov Y, Lutsik P, Stilgenbauer S, Roessner PM, Seiffert M, Byrd J, Oakes CC, Plass C, Lipka DB (2020) Methylome-based cell-of-origin modeling (Methyl-COOM) identifies aberrant expression of immune regulatory molecules in CLL. Genome Med 12, 29. doi: 10.1186/s13073-020-00724-7 | Abstract | Reprint (5.0 MB) | Article metrics
Erdel F, Rademacher A, Vlijm R, Tünnermann J, Schweigert E, Frank L, Yserantant K, Hummert J, Bauer C, Schumacher S, Weinmann R, Alwash AA, Normand C, Herten D-P, Engelhardt J, Rippe K (2020) Mouse heterochromatin adopts digital compaction states without showing hallmarks of HP1-driven liquid-liquid phase separation. Mol Cell 78, 236-249.e7. doi: 10.1016/j.molcel.2020.02.005 | Abstract | Reprint (6.2 MB) | Article metrics | Comment
Sieverling L, Hong C, Koser SD, Ginsbach P, Kleinheinz K, Hutter B, Braun DM, Cortes-Ciriano I, Xi R, Kabbe R, Park PJ, Eils R, Schlesner M, PCAWG-Structural Variation Working Group, Brors B, Rippe K, Jones DTW, Feuerbach L, PCAWG Consortium (2020) Genomic footprints of activated telomere maintenance mechanisms in cancer. Nat Commun 11, 733. doi: 10.1038/s41467-019-13824-9 | Abstract | Reprint (2.2 MB) | Article metrics
ICGC/TCGA Pan-Cancer Analysis of Whole Genomes Consortium (2020) Pan-cancer analysis of whole genomes. Nature 578, 82-93. doi: 10.1038/s41586-020-1969-6 | Abstract | Reprint (23.6 MB) | Article metrics
Mallm JP, Windisch P, Biran A, Schumacher S, Glass R, Herold-Mende C, Meshorer E, Barbus M, Rippe K (2020) Glioblastoma initiating cells are sensitive to histone demethylase inhibition due to loss of DNA repair capacity. Intl J Cancer 146, 1281-1292. doi: 10.1002/ijc.32649 | Abstract | Reprint (6.6 MB) | Article metrics
Hoflmayer D, Steinhoff A, Hube-Magg C, Kluth M, Simon R, Burandt E, Tsourlakis MC, Minner S, Sauter G, Buscheck F, Wilczak W, Steurer S, Huland H, Graefen M, Haese A, Heinzer H, Schlomm T, Jacobsen F, Hinsch A, Poos AM, Oswald M, Rippe K, Konig R, Schroeder C (2020) Expression of CCCTC-binding factor (CTCF) is linked to poor prognosis in prostate cancer. Mol Oncol14, 129-138. doi: 10.1002/1878-0261.12597 | Abstract | Reprint (10.5 MB) | Article metrics
Abstracts
Tirier SM, Mallm J-P, Casiraghi N, Susak H, Giesen N, Poos A, Bauer K, Baumann A, John L, Xu J, Klett L, Müller-Tidow C, Brors B, Goldschmidt H, Weinhold N, Stegle O, Rippe K, Raab MS (2019) Dissecting heterogeneity of tumor cells and their microenvironment in refractory multiple myeloma. Blood 134, 571. doi: 10.1182/blood-2019-128625 | Abstract
Poos AM, Mallm J-P, Tirier SM, Casiraghi N, Susak H, Giesen N, Bauer K, Baumann A, John L, Lander I, Xu J, Przybilla M, Kunze A, Mueller-Tidow C, Brors B, Stegle O, Goldschmidt H, Rippe K, Raab MS, Weinhold N (2019) A comprehensive analysis of intra-tumor heterogeneity and treatment responses in relapsed/refractory multiple myeloma patients using single cell sequencing approaches. Blood 134, 575. doi: 10.1182/blood-2019-130051 | Abstract
Staeble S, Kraemer S, Langstein J, Bogeska R, Hartmann M, Schoenung M, Czeh M, Knoch J, Anstee N, Haas S, Mahmoud A, Graesel J, Huebschmann D, Feuerbach L, Dieter W, Brors B, Rippe K, Mallm J-P, Rosenbauer F, Plass C, Schlesner M, Milsom MD, Lipka DB (2019) Deconvolution of Hematopoietic Commitment Decisions By Genome-Wide Analysis of Progressive DNA Methylation Changes. Blood 134, 1179. doi: 10.1182/blood-2019-124429 | Abstract
Selected recent publications 2014-2020 (more selected publications)
Erdel F, Rademacher A, Vlijm R, Tünnermann J, Schweigert E, Frank L, Yserantant K, Hummert J, Bauer C, Schumacher S, Weinmann R, Alwash AA, Normand C, Herten D-P, Engelhardt J, Rippe K (2020) Mouse heterochromatin adopts digital compaction states without showing hallmarks of HP1-driven liquid-liquid phase separation. Mol Cell 78, 236-249.e7. doi: 10.1016/j.molcel.2020.02.005 | Abstract | Reprint (6.2 MB) | Article metrics | Comment
Mallm JP, Windisch P, Biran A, Schumacher S, Glass R, Herold-Mende C, Meshorer E, Barbus M, Rippe K (2020) Glioblastoma initiating cells are sensitive to histone demethylase inhibition due to loss of DNA repair capacity. Intl J Cancer 146, 1281-1292. doi: 10.1002/ijc.32649 | Abstract | Reprint (6.6 MB) | Article metrics
Mallm JP, Iskar M, Ishaque N, Klett LC, Kugler SJ, Muino JM, Teif VB, Poos AM, Großmann S, Erdel F, Tavernari D, Koser SD, Schumacher S, Brors B, König R, Remondini D, Vingron M, Stilgenbauer S, Lichter P, Zapatka M, Mertens D & Rippe K (2019) Linking aberrant chromatin features in chronic lymphocytic leukemia to deregulated transcription factor networks. Mol Syst Biol 15, e8339. doi: 10.15252/msb.20188339 | Abstract | Reprint (7.1 MB) | Appendix (6.8 MB) | Additional data | Article metrics
Rademacher A, Erdel F, Trojanowski J, Schumacher S & Rippe K (2017). Real-time observation of light-controlled transcription in living cells. J Cell Sci 130, 4213-4224. doi: 10.1242/jcs.205534 | Abstract | Reprint (12.9 MB) | JCS First person | Article metrics
Wachsmuth M, Knoch TA & Rippe K (2016). Dynamic properties of independent chromatin domains measured by correlation spectroscopy in living cells. Epigenetics Chromatin 9, 57. doi: 10.1186/s13072-016-0093-1 | Abstract | Reprint (5.1 MB) | Article metrics.
Caudron-Herger M, Pankert T, Seiler J, Nemeth A, Voit R, Grummt I & Rippe K (2015). Alu element-containing RNAs maintain nucleolar structure and function. EMBO J 34, 2758-2771. doi: 10.15252/embj.201591458 | Abstract | Reprint (4.6 MB) | Comment | Cover | Article metrics
Mallm JP & Rippe K (2015). Aurora kinase B regulates telomerase activity via a centromeric RNA in stem cells. Cell Rep 11, 1667-1678. doi: 10.1016/j.celrep.2015.05.015 | Abstract | Reprint (5.9 MB) | Article metrics
Osterwald S, Deeg KI, Chung I, Parisotto D, Wörz S, Rohr K, Erfle H & Rippe K (2015). PML induces compaction, partial TRF2 depletion and DNA damage signaling at telomeres and promotes alternative lengthening of telomeres. J Cell Sci 128, 1887-1900. doi: 10.1242/jcs.148296 | Abstract | Reprint (4.3 MB) | Article metrics
Müller-Ott K, Erdel F, Matveeva A, Hahn M, Mallm, JP, Rademacher A, Marth C, Zhang Q, Kaltofen S, Schotta G, Höfer T & Rippe K (2014). Specificity, propagation and memory of pericentric heterochromatin. Mol Syst Biol 10, 746. doi: 10.15252/msb.20145377 | Abstract | Reprint (7.4 MB) | Article metrics
Baum M, Wachsmuth M, Erdel F & Rippe K (2014). Retrieving the intracellular topology from multi-scale protein mobility mapping in living cells. Nat Commun 5, 4494. doi: 10.1038/ncomms5494 | Abstract | Reprint (6.4 MB) | Article metrics
Teif VB, Beshnova DA, Vainshtein Y, Marth C, Mallm JP, Höfer T & Rippe K (2014). Nucleosome repositioning links DNA (de)methylation and differential CTCF binding during stem cell development. Genome Res 24, 1285-1295. doi: 10.1101/gr.164418.113 | Abstract | Reprint (3.3 MB) | Article metrics
All publications 1989-2020
All publications h-index Karsten Rippe: 60 (Google Scholar)
- Research articles in peer reviewed journals (135 articles)
- Reviews and book chapters (peer reviewed) (28 articles)
- Selected publications
- Other publications (6 articles)
- PhD theses (17), diploma/master theses (15) and patents (2)
Publications and bibliometric data of Karsten Rippe from databases
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Yearly citation numbers of Karsten Rippe from 2006 to 2020. Total number of citations: 10978, h-index: 55, i10 index: 127. Bibliometric data are taken from Google Scholar.
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