The interior of a cell from a moving protein's point of view
July 2014 - Numerous obstacles posed by cellular subcompartments and structures constrain protein transport in the cell. We mapped the intracellular topology the intracellular topology by tracing fluorescently labeled reporter proteins in living cells on multiple time and length scales more...

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Genome Organization & Function

Research focus

The Genome Organization & Function group at the BioQuant is an interdisciplinary research team from the German Cancer Research Center (DKFZ). We combine molecular/cell biology and physics to develop quantitative descriptions that relate the dynamic organization of the (epi)genome with gene expression programs and functional cell states.

RNA in Chromatin Structure Epigenetic Networks Alternative Lengthening of Telomeres Chromatin Remodelers Chromatin Fibers Fluorescence Imaging Modeling of DNA Accessibility Single Cell Manipulations Fluctuation Microscopy Deep Sequencing

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