RNA glue for the protein assembly line
October 10, 2015 - The paper by Maiwen and Teresa on intronic Alu repeat containing RNAs are needed to keep the nucleolus in shape has been published in The EMBO Journal, along with a News & Views article and a cover image. more...

CSB2 Prize in Sysctems Biology
July 8, 2015 - Karsten Rippe was laureate of the CSB2 Prize sponsored by Merrimack Pharmaceuticals. more...

Alternative routes to immortality
June 12, 2015 - Every time a cell divides, the ends of chromosomes - the threads of DNA residing in the nucleus - shorten a bit. Once the chromosome ends, called telomeres, become too short, cells normally stop dividing. Read on how cancer cells make use of specific DNA repair enzymes to extend the telomeres. more...

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Genome Organization & Function

Research focus

The Genome Organization & Function group at the BioQuant is an interdisciplinary research team from the German Cancer Research Center (DKFZ). We combine molecular/cell biology and physics to develop quantitative descriptions that relate the dynamic organization of the (epi)genome with gene expression programs and functional cell states.

RNA in Chromatin Structure Epigenetic Networks Alternative Lengthening of Telomeres Chromatin Remodelers Chromatin Fibers Fluorescence Imaging Modeling of DNA Accessibility Single Cell Manipulations Fluctuation Microscopy Deep Sequencing

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