BIOQUANT
News

Get ready for the scOpenLab
Jan 2, 2018 - The new DKFZ "Open Lab" for sequencing single cell headed by Philipp Mallm will start in January. We are excited to set up state of the art instrumentation and protocols for different single cell sequencing readouts. more...

Optogenetics in the cell nucleus: "My brain just BLinCRed"
Dec 15, 2017 - Our paper on using an optogenetics approach to trace transcription activation in living cells in real-time has been published now in the Journal of Cell Science. more...

Welcome to the "Professorium"
Nov 15, 2017 - Karsten Rippe had his official introduction as a full professor at the University of Heidelberg. more...

more news...

Chromatin Networks

Research focus

The Chromatin Networks division is an interdisciplinary research team at the Bioquant and the German Cancer Research Center (DKFZ). We combine molecular/cell biology and physics to develop quantitative descriptions that relate the dynamic organization of the (epi)genome with gene expression programs and functional cell states. Our research comprises the four main areas epigenetic regulation, nuclear organization, chromatin in leukemia and telomere maintenance, which we investigate with a set of complementary methods as depicted in the scheme below.

 

Chromatin Editing Network Modeling Telomere Maintenance Single Cell Sequencing Chromatin in Leukemia Nuclear Organization Quantitative Microscopy Epigenetic Regulation